Xylitol was discovered by Nobel Prize winner Emil Fischer around 1900 and has been used in foods since the 1960's and has been used widely as a popular sweetener in diabetic diets. Xylitol is a natural sweetener that reduces plaque-forming bacteria, remineralizes tooth enamel, and stimulates the production of saliva for dry mouth. Xylitol can have a particularly long term positive effect on the oral well being of children under the age of 12. Use miradent Xylitol chewing gum immediately after eating and chew until the taste disappears. The use should be spread out over the day. Adults: 3 to 5 times/day X 2 tablets; Children 3 to 5 times/day X 1 tablet.